Albumin Globulin Ratio Calculator | A/G Ratio (2024)

FAQs

Is a 2.4 A/G ratio bad? ›

A test result with a ratio less than 1 or more than 2.5 is considered bad. A bad ratio means the presence of an ongoing disease or pathology in the body. What does the AG ratio indicate? The AG ratio indicates the concentration of albumin and globulins in the blood serum of an individual.

To determine the A/G Ratio, the concentration of albumin and globulins in the blood is measured; subsequently, the A/G Ratio is calculated by dividing the albumin concentration by the globulin concentration. Fasting is typically required for this test.

The normal range for albumin/globulin ratio is over 1 , usually around 1 to 2. That's because there's a bit more albumin than globulin in serum protein. If your body is producing too much or too little of either protein, your A/G ratio will be classified as high or low.

Low A/G ratio: This might be the sign an autoimmune disorder, where your body's immune system attacks healthy cells. It can also point to kidney disease or cirrhosis, which is inflammation and scarring of the liver. In some cases, a low A/G ratio can be a sign of a tumor in your bone marrow.

Results more than 3.5 g/dL for globulin and more than 2.5 for an albumin/globulin ratio are considered high. But being on bed rest for too long, dehydration, and problems during the blood draw can also cause a high reading. Your healthcare provider will likely order additional tests.

Taking Action for Optimal A/G Ratio

Nutrition: A balanced diet rich in nutrients supports both albumin and globulin synthesis. Adequate protein intake, along with a variety of vitamins and minerals, contributes to a healthy A/G ratio.

A high A/G ratio may indicate kidney disease, antibody deficiencies, or severe dehydration. A low A/G ratio can also indicate kidney disease as well as liver disease, chronic infections like human immunodeficiency virus (HIV), autoimmune diseases like lupus, and certain cancers.

The Albumin/Globulin ratio in the total protein test will help assess the general health of the patient, and this index may suggest liver and kidney related diseases and assess liver function. . The albumin/globulin ratio in patients will usually be in the 1-1.5 range.

Normal value ranges are: Serum globulin: 2.0 to 3.5 grams per deciliter (g/dL) or 20 to 35 grams per liter (g/L) IgM component: 75 to 300 milligrams per deciliter (mg/dL) or 750 to 3,000 milligrams per liter (mg/L) IgG component: 650 to 1,850 mg/dL or 6.5 to 18.50 g/L.

What cancers cause high protein in the blood? ›

Normal albumin levels in an adult's blood range from 3.5 to 5.5 grams per deciliter (g/dL). Lower-than-normal albumin levels in your blood (hypoalbuminemia) may indicate: Infection.

If your A/G ratio was low, it may be caused by:

An autoimmune disease, such as lupus. Liver disease, including cirrhosis.

Low albumin levels can be a sign of liver or kidney disease or another medical condition. High levels may be a sign of dehydration. Albumin is a protein made by your liver. Albumin enters your bloodstream and helps keep fluid from leaking out of your blood vessels into other tissues.

Total serum protein = Albumin + Globulin Globulin =Total serum protein – Albumin = 6.82- 3.93 = 2.89 gm/dL So, A/G ratio = Albumin / Globulin = 3.93 / 2.89 A/G ratio = 1.35 gm/dL (Ans.)

Normal Results

Normal value ranges are: Serum globulin: 2.0 to 3.5 grams per deciliter (g/dL) or 20 to 35 grams per liter (g/L) IgM component: 75 to 300 milligrams per deciliter (mg/dL) or 750 to 3,000 milligrams per liter (mg/L)

High blood protein is not a specific disease or condition, but it might indicate you have a disease. High blood protein rarely causes symptoms on its own. But sometimes it is uncovered while you're having blood tests done for a separate issue or symptom.

If your total protein level is low, you may have a liver or kidney problem, or it may be that protein isn't being digested or absorbed properly. A high total protein level could indicate dehydration or a certain type of cancer, such as multiple myeloma, that causes protein to accumulate abnormally.

Globulin and albumin are proteins found in the blood. Levels that are too high can indicate autoimmune disease, infections or cancers. Low levels may be a sign of liver or kidney problems. Your provider will order additional tests to make a diagnosis.