Albumin Globulin Ratio Calculator | A/G Ratio (2024)

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What is A G ratio?What is the albumin globulin ratio used for? 🤔What is a normal AG ratio?What does a high AG ratio mean?How to calculate albumin globulin ratio?FAQs

Welcome to the albumin globulin ratio calculator! We'll show you everything you need to know about the AG ratio meaning and the AG ratio blood test. 💉

We won't stop at basic definitions — keep on reading to:

  • Learn more about the different proteins in our body;
  • Find out how to calculate albumin globulin ratio; and
  • Discover the normal albumin globulin ratio ranges.

❗ The albumin globulin ratio calculator cannot be used as a substitute for clinical knowledge and/or consultation with a medical specialist. Always consult your doctor.

What is A G ratio?

The AG ratio is the abbreviation for the albumin globulin ratio, sometimes called the alb glob ratio. It's obtained with a quick test performed on a blood sample. This proportion tells us about the relation of two important proteins in our body:

  • Albumins are the most common proteins in human blood. They bind to different substances and regulate the oncotic and osmotic pressure. Their normal range is 3.5–5.2 g/dL.
  • Globulins are produced by the liver and the immunological system (antibodies!). They have higher protein molecular weight than albumins. Their normal range equals 2.6–3.5 g/dL.

What is the albumin globulin ratio used for? 🤔

The physicians use the A/G ratio to diagnose different diseases associated with abnormally low or high levels of proteins and/or check for eventual malnutrition. The list of possible disorders is long and may include dehydration, HIV/AIDS, kindey failure or liver failure.

Want to know more about the liver damage? Why don't you start with the AST ALT ratio calculator. 📍

What is a normal AG ratio?

The albumin globulin ratio's normal range varies depending on the quoted source — it's been reported as either:

  • 1.2–2.2;
  • 1.5–2.5;
  • 0.5–1.2; or
  • 1.1–2.5.

Usually, a A G ratio of 1.0 or less is considered significant. The same goes for values over 2.5. Consult your local laboratory on their specific ranges.

What does a high AG ratio mean?

The meaning of a A high A/G ratio depends on the state of the patient, their signs, symptoms and reported complaints.

Let's say that your AG ratio is 2.5, meaning it's way too high than it should be. Let's look at all the disorders that may be responsible for this result:

  • Dehydration (high levels of albumin, due to lack of water);
  • Leukemia (impaired globulin production);
  • Immunodeficiency, e.g., HIV or genetic disorders (impaired globulin production); or
  • Drug interactions.

How to calculate albumin globulin ratio?

We can help you with this simple task! The formula you need looks as follows:

A/G Ratio = Albumin / (Total protein − Albumin)

Where both Albumin and Total protein are given in g/dL.

Happy with our AG ratio calculator? We have plenty of amazing ratio tools to discover — like:

  • The protein creatinine ratio calculator that helps to determine the proteinuria; and
  • The article that will acknowledge you with CKD stages and albuminuria - the albumin creatinine ratio calculator.

How do I calculate the AG ratio if my Albumin is 4 g/dL?

To calculate the A/G ratio with an albumin level of 4 g/dL, assuming a total protein level is 7 g/dL, follow these steps:

  1. Subtract the albumin level (4 g/dL) from the total protein (7 g/dL).
  2. Divide the albumin level (4 g/dL) by the difference obtained in step 1 (3 g/dL).
  3. That's all! You have now determined that the A/G ratio is 1.3333.

What does it mean to have the AG ratio of 1.0?

Usually, a ratio of 1 is considered to be too low. A low A/G ratio might be indicative of:

  • Inflammation (overproduction of globulin);
  • Liver disease (impaired production of albumin);
  • Kindey disease, e.g., nephrotic syndrome (loss of albumin in urine);
  • Autoimmune disease (excessive production of immunoglobulin — antibodies); or
  • Myeloma (excessive production of immunoglobulin — antibodies).

What does it mean to have the AG ratio of 2.4?

The A/G ratio of 2.4 is considered to be high. Elevated AG ratios can be associated with various medical conditions, including dehydration, leukemia, immunodeficiency, and specific drug interactions. If you have received a blood test result indicating a high A/G ratio, it's essential to consult with a healthcare provider for a comprehensive evaluation.

How is the AG ratio obtained?

The A/G ratio (short for the Albumin-Globulin ratio) is obtained through a blood test. The indicator provides essential information about the balance of two critical proteins in your body – albumin and globulin. To calculate your A/G ratio and learn more, visit the Omni albumin globulin ratio calculator!

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Albumin Globulin Ratio Calculator | A/G Ratio (2024)


Is a 2.4 A/G ratio bad? ›

A test result with a ratio less than 1 or more than 2.5 is considered bad. A bad ratio means the presence of an ongoing disease or pathology in the body. What does the AG ratio indicate? The AG ratio indicates the concentration of albumin and globulins in the blood serum of an individual.

How to calculate albumin globulin ratio? ›

To determine the A/G Ratio, the concentration of albumin and globulins in the blood is measured; subsequently, the A/G Ratio is calculated by dividing the albumin concentration by the globulin concentration. Fasting is typically required for this test.

What is a normal Ag ratio level for a woman? ›

The normal range for albumin/globulin ratio is over 1 , usually around 1 to 2. That's because there's a bit more albumin than globulin in serum protein. If your body is producing too much or too little of either protein, your A/G ratio will be classified as high or low.

Should I worry if my Ag ratio is low? ›

Low A/G ratio: This might be the sign an autoimmune disorder, where your body's immune system attacks healthy cells. It can also point to kidney disease or cirrhosis, which is inflammation and scarring of the liver. In some cases, a low A/G ratio can be a sign of a tumor in your bone marrow.

What is an alarming globulin level? ›

Results more than 3.5 g/dL for globulin and more than 2.5 for an albumin/globulin ratio are considered high. But being on bed rest for too long, dehydration, and problems during the blood draw can also cause a high reading. Your healthcare provider will likely order additional tests.

How to improve ag ratio? ›

Taking Action for Optimal A/G Ratio

Nutrition: A balanced diet rich in nutrients supports both albumin and globulin synthesis. Adequate protein intake, along with a variety of vitamins and minerals, contributes to a healthy A/G ratio.

What is the most common cause of high Ag ratio? ›

A high A/G ratio may indicate kidney disease, antibody deficiencies, or severe dehydration. A low A/G ratio can also indicate kidney disease as well as liver disease, chronic infections like human immunodeficiency virus (HIV), autoimmune diseases like lupus, and certain cancers.

What is the albumin globulin ratio for fatty liver? ›

The Albumin/Globulin ratio in the total protein test will help assess the general health of the patient, and this index may suggest liver and kidney related diseases and assess liver function. . The albumin/globulin ratio in patients will usually be in the 1-1.5 range.

What is a normal globulin level in a woman? ›

Normal value ranges are: Serum globulin: 2.0 to 3.5 grams per deciliter (g/dL) or 20 to 35 grams per liter (g/L) IgM component: 75 to 300 milligrams per deciliter (mg/dL) or 750 to 3,000 milligrams per liter (mg/L) IgG component: 650 to 1,850 mg/dL or 6.5 to 18.50 g/L.

What are the symptoms of too much protein in your blood? ›

Common symptoms associated with High Blood Protein may include the following.
  • Fatigue and weakness.
  • Unexplained weight loss.
  • Swelling in the extremities.
  • Changes in urine colour or frequency.
  • Abdominal pain or discomfort.
  • Loss of appetite.
Jan 17, 2024

What cancers cause high protein in the blood? ›

What causes high blood protein?
  • Dehydration.
  • Chronic (long-term) inflammation or inflammatory disorders.
  • Viral infections such as hepatitis B, hepatitis C or HIV/AIDS.
  • Blood cancers such as multiple myeloma or certain types of lymphoma.
  • Severe liver or kidney disease.
Oct 11, 2022

What is a normal albumin level for a woman? ›

Normal albumin levels in an adult's blood range from 3.5 to 5.5 grams per deciliter (g/dL). Lower-than-normal albumin levels in your blood (hypoalbuminemia) may indicate: Infection.

What autoimmune disease causes low ag ratio? ›

If your A/G ratio was low, it may be caused by:

An autoimmune disease, such as lupus. Liver disease, including cirrhosis.

What does it mean if albumin ratio is low? ›

Low albumin levels can be a sign of liver or kidney disease or another medical condition. High levels may be a sign of dehydration. Albumin is a protein made by your liver. Albumin enters your bloodstream and helps keep fluid from leaking out of your blood vessels into other tissues.

How do you calculate a G ratio? ›

Total serum protein = Albumin + Globulin Globulin =Total serum protein – Albumin = 6.82- 3.93 = 2.89 gm/dL So, A/G ratio = Albumin / Globulin = 3.93 / 2.89 A/G ratio = 1.35 gm/dL (Ans.)

Is 3.6 globulin level high? ›

Normal Results

Normal value ranges are: Serum globulin: 2.0 to 3.5 grams per deciliter (g/dL) or 20 to 35 grams per liter (g/L) IgM component: 75 to 300 milligrams per deciliter (mg/dL) or 750 to 3,000 milligrams per liter (mg/L)

Should I be worried about slightly high protein in blood? ›

High blood protein is not a specific disease or condition, but it might indicate you have a disease. High blood protein rarely causes symptoms on its own. But sometimes it is uncovered while you're having blood tests done for a separate issue or symptom.

Can low protein in blood be serious? ›

If your total protein level is low, you may have a liver or kidney problem, or it may be that protein isn't being digested or absorbed properly. A high total protein level could indicate dehydration or a certain type of cancer, such as multiple myeloma, that causes protein to accumulate abnormally.

Should I worry if my globulin is high? ›

Globulin and albumin are proteins found in the blood. Levels that are too high can indicate autoimmune disease, infections or cancers. Low levels may be a sign of liver or kidney problems. Your provider will order additional tests to make a diagnosis.


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